Ketogenic diet glioblastoma multiforme in addition to potent in weight loss, this has indeed been known to have many health benefits. One of the benefits is to deactivate the cancer cells so it does not grow and spread throughout the body. Several studies have been done to see the effectiveness of keto diet against cancer cells, especially brain cancer.
And the results prove that ketogenic diet glioblastoma multiforme can help inhibit tumor growth. How does this diet handle the growth of glioblastoma multiforme? But before, let’s first discuss what is glioblastoma multiforme.
Ketogenic Diet Glioblastoma Multiforme Understanding
What is glioblastoma multiforme? Glioblastoma multiforme is the most aggressive and often found malignant primary brain tumor. Glioblastoma multiforme involves glia cells and is responsible for 52% of cases of functional brain tissue tumors and 20% intracranial tumors. MFH is one type of glia cells that arise from astrocytes. Until now unknown what factors affect astrocytes and how they degenerate into cancer cells. This brain tumor is one of five cancers with the lowest life expectancy compared to other types of cancer in the world.
Patients with glioblastoma multiforme have various symptoms. Symptoms include recurrent headache (occurring in more than 30% of patients), recurrent attacks (occurring in 20% – 30% of patients), progressive cognitive dysfunction (these symptoms depend on the location of the tumor), problems with the senses (sight, speech) and motor functions, personality changes (inappropriate behavioral development), and memory loss.
One treatment that is able to inhibit the growth and spread of cancer cells is keto diet. Although not many, there are some studies that have proven it.
What is keto diet?
Keto diet is not a new diet method. This diet has been around since the 1920s and was developed by John Hopkins Medical Center as a treatment for epilepsy in children. This diet is proven to reduce the symptoms of seizures in patients with epilepsy> 50%. Keto diet is a diet that carries intake of foods containing high fat, medium protein, and low carbohydrates with a ratio of 75%: 20%: 5%. The goal is to make the body go into ketosis conditions. Ketosis is a condition in which the body uses ketones (derived from fat) instead of glucose in metabolic processes.
The keto diet has benefits for losing weight and preventing and treating certain diseases. One of the diseases that can be prevented and handled by this diet is cancer, especially brain cancer. Research in 2007 was conducted to determine the effectiveness of low carbohydrate diet in cancer. The study was conducted on mice that have been implanted malignant brain cancer cells. The first group of mice fed a diet high in fat and low carbohydrates while the second group of mice given a diet high in carbohydrates and low in fat. The results obtained that the first group experienced a decrease in brain tumor growth of about 35 – 65%, (depending on the tumor line). In addition, the diet in the first group significantly improved the health and survival of rats compared to the group that was given a high carbohydrate and low-fat intake.
Another study conducted in 2010 in elderly women with glioblastoma multiforme who perform keto diet accompanied by fasting. The results showed a decrease in the tumor during treatment, and the smaller the next scan. This is done to the point where the patient stops following the diet. After the keto diet is stopped, the brain tumor increases again.
Ketogenic Diet Glioblastoma Multiforme Handling
Until now there is no medical equipment that can detect the cause of cancer cells appear. Some say cancer cells come from free radicals, lack of antioxidants, radiation, and so on. Cancer cells have properties that are different from normal cells in the body. In cancer cells division occurs irregularly, eat other cell nutrients, and do not require oxygen again because mitochondria are not there.
The shape of cancer cells is similar to cells in viruses and bacteria. They expand and divide by 50% of their original size in a faster time than normal cells, splitting speed even. That’s why cancer cells are called “anabolic cells”. The rapid cleavage and development of automatic cancer cells make them require high fuel to receive energy. In obtaining energy, cancer cells can only metabolize glucose. So that cancer patients are strongly recommended to reduce carbohydrate intake.
Keto diet is a diet method that carries a low carbohydrate intake so that it changes metabolism by making ketones as a source of energy rather than glucose. This condition is called ketosis and then helps lower blood glucose, increases the enzyme known as blood ketone, and makes glioblastoma multiforme more responsive to chemotherapy and radiotherapy.
The ketogenic diet method does not require medication and is a natural therapy that does not disrupt the body’s metabolism in general and continues to be developed for cancer prevention and treatment. An important key to the treatment of cancer with diet is the limiting intake of glucose in which cancer cells rely heavily on it. When the consumption of carbohydrates and sugars is not reduced, the energy produced will be more widely used by cancer cells. This is because cancer cells are stronger than normal cells.
In the study, glioblastoma multiforme responded to patients treated with the keto diet, which decreased the regulatory gene that triggered the tumor, and the keto diet changed the tumor phenotype sign to normal cells. Healthy brain cells can receive the intake of energy coming from either glucose or ketones. When the body is in ketosis, glucose is absent and the brain only accepts energy intake from ketones. Therefore, cancer cells that depend only on glucose eventually do not receive energy intake because they cannot absorb ketones. This condition will make cancer cells starve and eventually inhibit the growth and spread throughout the body.
In addition, to deactivate cancer cells must be considered also the daily food intake. Find out what foods are suitable for consumption during keto diet and what should be limited or avoided. Feed intake is good and according to the rules, keto diet will facilitate the body into ketosis conditions.
Sample Diet Menu for Ketogenic Diet Glioblastoma Multiforme
If you have trouble or are confused about how to plan the right food menu during keto diet, here are some examples of eating menus that you can copy at home. Although the menu is recommended, remember the ratio of fat, protein, and carbohydrates!
- Menu 1
Breakfast: sugar-free yoghurt with peanut butter, cocoa powder and stevia
Lunch: chicken salad with olive oil and feta cheese
Dinner: salmon, eggs, and spinach cooked with coconut oil
Snacks: boiled eggs
- Menu 2
Breakfast: milkshake keto
Lunch: Prawn salad with olive oil and avocado
Dinner: meatballs, cheddar cheese and vegetables
Snacks: 90% dark chocolate
- Menu 3
Breakfast: omelet, ham and cheese with vegetables
Lunch: almond milk, cocoa powder, peanut butter and stevia milkshake
Dinner: salmon and asparagus cooked with butter
Snacks: keto ice cream
- Menu 4
Breakfast: meats, eggs, and tomatoes
Lunch: a handful of nuts and celery with guacamole and salsa
Dinner: steak and eggs with a little salad.
Snacks: a handful of nuts or seeds
You can eat snacks in the morning or afternoon. In addition to the above snacks, you can also consume cheese, meat or fatty fish, low-carb milkshakes (with almond milk, chocolate powder and peanut butter), full-fat yoghurt (with peanut butter and cocoa powder), strawberries and cream, celery with salsa and guacamole, olives, and soybean bar snack.
Maybe for cancer patients, to do keto diet is not easy because the body must adjust to the metabolic processes that change. But research has been done on the ketogenic diet of glioblastoma multiforme and the results are positive for treating cancer. So, it’s good if you are cancer patients try this ketogenic diet glioblastoma multiforme method, of course after consultation with a doctor first. Good luck and hopefully get well soon!
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